Cytokine Polymorphisms and Severity of Tubal Damage in Women withChlamydia‐Associated Infertility
نویسندگان
چکیده
منابع مشابه
Cytokine profile in Nigerians with tubal infertility.
INTRODUCTION Immune response to genital Chlamydia trachomatis infection is involved in both immunity and pathology. The cytokine profile during infection has been implicated in the disease outcome, either resolution or severe sequelae. Serum cytokines of Chlamydia positive Nigerian women with tubal infertility were assessed to determine their possible relationship with tubal occlusion. MATERI...
متن کاملTubal Damage, Infertility and Tubal Ectopic Pregnancy: Chlamydia trachomatis and Other Microbial Aetiologies
Infertility is a worldwide health problem with one in six couples suffering from this condition and with a major economic burden on the global healthcare industry. Estimates of the current global infertility rate suggest that 15% of couples are infertile (ZegersHochschild et al., 2009) defined as: (1) failure to conceive after one year of unprotected sexual intercourse (i.e. infertility); (2) c...
متن کاملEffect of IL12A and IL12B polymorphisms on the risk of Chlamydia trachomatis-induced tubal factor infertility and disease severity.
BACKGROUND Interleukin-12 (IL-12) and related cytokines induce activation and differentiation of T cells. Our aim was to investigate the associations between genetic differences in IL-12-family cytokines and the pathogenesis of chlamydial disease. METHODS The final study population consisted of 100 women with Chlamydia trachomatis-induced tubal factor infertility (TFI) and 125 pregnant women ...
متن کاملFluoroscopic tubal recanalization in tubal factor related infertility.
Infertility is defined as the inability to conceive after 1 year of unprotected intercourse, a definition that is based on a monthly fecundity rate of 15 to 25%. Approximately 10 to 20% of couples may experience problems conceiving, and infertility can result from a wide variety of etiologies. Female factors account for 40% of infertility.1 When investigating infertility, evaluation of both the...
متن کاملTubal damage in infertile women: prediction using chlamydia serology.
BACKGROUND The study explores the relationship between serum chlamydia antibody titres (CATs) and detection of tubal damage in infertile women. METHODS The tubal status and pelvic findings in 1006 women undergoing laparoscopy for infertility were related to CAT, which was measured using the whole-cell inclusion immunofluorescence test. RESULTS A negative correlation between CAT and age was ...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2009
ISSN: 0022-1899,1537-6613
DOI: 10.1086/597620